A fatal crash on U.S. Highway 40 in Fraser closed the highway for about 4 hours, Thursday, Dec. 26.

One person was killed in the crash, which was reported at 9:25 a.m. Thursday, Dec. 26, and took place at mile post 228, according to a news release from the Fraser Winter Park Police Department. Four others sustained “significant injuries” and were transported by Grand County EMS to Middle Park Medical Center in Granby and Denver Health East Grand Community Clinic in Winter Park. One injured person was expected to be transported to a Denver-area hospital, according to the release.

The highway was closed from Kings Crossing to Old Victory Road in Fraser throughout the crash investigation, according to a Facebook post by the Fraser Winter Park Police Department. During the closure, traffic was being redirected to Old Victory Road. The road reopened at about 1:37 p.m.

The crash involved a semitrailer, according to CoTrip.org.

Colorado State Patrol and the Grand County Coroner’s Office assisted in the crash investigation, according to the release.

It was the second crash to close U.S. 40 in Grand County in less than 24 hours. Another collision Wednesday, Dec. 25, closed the highway between Fraser and Tabernash for about 2 1/2 hours, from 5:41-8:17 p.m., according to Colorado State Patrol spokesperson Gabriel Moltrer.

The crash was a head-on collision that resulted in multiple injuries, with at least one person being transported to the hospital. Motorists were directed to use Grand County Road 5 during the closure.

Snow showers Christmas Day created slick travel conditions along U.S. 40 and other roads in Grand County.